99% Purity Sarms Powder CAS 317318-84-6 Gw-0742/Gw610742


Quick Detail:

Product Name	GW0742
CAS	317318-84-6
Synonyms	GW0742; [4-[[[2-[3-FLUORO-4-(TRIFLUOROMETHYL)PHENYL]-4-METHYL-5-THIAZOLYL]METHYL]THIO]-2-METHYLPHENOXY]ACETIC ACID; 4-[2-(3-FLUORO-4-TRIFLUOROMETHYL-PHENYL)-4-METHYL-THIAZOL-5-YLMETHYLSULFANYL]-2-METHYL-PHENOXY-ACETIC ACID; 4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]AceticAcid; 4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]- 2-methyl-phenoxy}-acetic acid; Acetic acid, 2-[4-[[[2-[3-fluoro-4-(trifluoroMethyl)phenyl]-4-Methyl-5-thiazolyl]Methyl]thio]-2-Methylphenoxy]-; 2-(4-(((2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methyl)thio)-2-methylphenoxy); GW 0742X
Alias	Testosterone Cyclopentylpropionate
Purity	98%
MF	C21H17F4NO3S2
MW	471.49
mp	134.5-135.5 °C
storage temp	2-8°C
Color	Light Yellow
Appearance	Light Yellow Solid
Brand	NJBN STEROID
Price	Negotiated
Shipment	EMS, FedEx, TNT, DHL, UPS
Delivery	within 1 day after we get the payment
Product Categories	AllInhibitors; Inhibitors; Intermediates& FineChemicals; Pharmaceuticals; Intracellular receptor; Inhibitor
Usage	A small molecule agonist of the human Peroxisome Proliferator-Activated Recept d (PPAR d). It shows an EC50 of 1.1 nM against PPAR d with 100-fold selectivity over the other human subtypes

Product Description:

1. GW0742 is a synthetic, potent and selective PPAR-agonist. PPARs are ligand-dependent transcription factors which are involved in many physiological processes, such as inflammation and energy homeostasis. PPAR-is one of three PPARs in the nuclear hormone receptor superfamily that are collectively involved in the control of lipid homoeostasis among other functions. GW0742 can attenuate the increase of PARP activity that caused by SAO shock. GW0742 is also able to prevent radiation-induced brain injury in C57Bl/6 wild-type (WT) and PPAR knockout (KO) mice. Dietary GW0742 can prevent the acute increase in IL-1 mRNA and ERK phosphorylation measured at 3 h after a single 10-Gy dose of WBI as well as the increase in the number of activated hippocampal microglia 1 week after WBI.
Reference
Rosanna Di Paola, Emanuela Esposito, Emanuela Mazzon, Irene Paterniti, Maria Galuppo, Salvatore Cuzzocrea. GW0742, a selective PPAR-agonist, contributes to the resolution of inflammation after gut ischemia/reperfusion injury. August 2010. Journal of Leukocyte Biology. vol. 88 no. 2 291-301
Caroline I. Schnegg, Dana Greene-Schloesser, Mitra Kooshki, Valerie S. Payne, Fang-Chi Hsud, Mike E. Robbins. Hippocampal-dependent cognitive impairment after whole-brain irradiation. Free Radical Biology and Medicine. Volume 61, August 2013, Pages 1-9.

Order Guide

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Packaging & Delivery Process:

1. Payment Method: Western Union , Money Gram , T/T , Bitcoin

2. Minimum Order: 40-100g. As for oil steroids , MOQ is 50ml

3. Delivery: By courier ( EMS , DHL , Fedex , UPS , TNT) is preferrable , bulk order can be negotiable

4. Dispatch time: within 24h after comfirming payment

5. Tracking number: can be offered to you within 24h

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