Product Name: Trilostane CAS: 13647-35-3
Synonyms: TRILOSTANE; (2-alpha, 4-alpha, 5-alpha, 17-beta)-4,5-epoxy-17-hydroxy-3-oxoandrostane-2-car; 17-beta)-ph; 4-alpha, 5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril; 4-alpha, 5-epoxy-3,17-dihydroxy-5-alpha-androst-2-ene-2-carbonitrile; 4-alpha-5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril; androstane-2-carbonitrile, 4,5-epoxy-17-hydroxy-3-oxo-, (2-alpha, 4-alpha, 5-al; modrenal
CAS: 13647-35-3
MF: C20H27NO3
MW: 329.43
EINECS: 237-133-0
Product Categories: Intermediates & Fine Chemicals; Pharmaceuticals; Steroids; Inhibitor; FULVICIN
mp 264 °C
storage temp. -20°C Freezer
treatment of Cushing's syndrome: Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome and primary hyperaldosteronism. These are both disorders where excess amounts of corticosteroid hormones are produced in the body. Corticosteroids are essential for the body to make use of carbohydrates, fats and proteins and for a normal response to stress. They are also necessary for the regulation of salt and water balance in the body. Trilostane helps prevent the production of corticosteroids, controlling the symptoms associated with these disorders.
Trilostane can also be useful in the treatment of breast cancer that has relapsed in women who have gone through menopause.
Chemical Properties Tan Crystals
Usage An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer
Usage antifungal, inhibits mitosis in metaphase .