Product Name: L-Thyroxine CAS: 51-48-9
Synonyms: 3,5,3', 5'-tetraiodothyronine; beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine; l-3,5,3', 5'-tetraiodothyronine; l-t4; o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin; o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine; t4(hormone); tetraiodothyronine
CAS: 51-48-9
MF: C15H11I4NO4
MW: 776.87
EINECS: 200-101-1
Product Categories: Amino Acids; Organics; Heterocyclic Compounds; Amino Acids & Derivatives; Intermediates & Fine Chemicals; Pharmaceuticals; Isotope Labeled Compounds; Aromatics; Isotope Labelled Compounds; SYNTHROID; Isolabel; Other APIs
mp 235 °C
alpha -5 o (1N NaOH: EtOH 1:2)
storage temp. 2-8°C
Water Solubility insoluble
Merck 9491
Chemical Properties Crystalline Solid
Usage antihypercholesterimic, thyromimetic
One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroi d hormone, but has been used to treat hyperlipidemia.