Anastrozole (Arimidex) CAS 120511-73-1

Name: Anastrozole (Arimidex)

Synonyms: ICI-D-1033; Arimidex; 1-[3,5-di-(1-methyl-1-cyano)-ethyl]-benzyl-1,2,4-triazole; Anastrazole; Anastrozole;
Tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile

CAS NO: 120511-73-1

Structural formula: C17H19N5

Molecular weight: 293.37

Appearance: an off-white color crystalline powder

Standard: Enterprise Standard , USP

Assay: 99%

Use: It can be used to the treatment of Breast cancer

Package: As required foil bag

Anastrozole COA:

ANALYSISSPECIFICATIONSRESULTS

ASSAY98.0%--102.0%99.7%

CHEMICAL CONTROL

IDENTIFICATIONIR HPLC reactiveConform with standard IR Conform with standard HPLC Conform

SOLUBILITYFreely soluble in methanol, acetone, ethanol and tetrahydrofuran. And very soluble in acetonitrileComplies

MELTING POINT81.0 ~ 84.0℃82.9 ~ 83.3℃

TOTAL IMPURIRY0.5%(max)0.20%

Total unspecified impurity0.2%(max)0.11%

Individual unspecified impurity0.1%(max)0.07%

Related compound B0.2%(max)0.05%

Related compound C0.2%(max)0.02%

Related compound D0.1%(max)0.06%

Related compound E0.1%(max)0.08%

LIMIT OF CYCLOHEXANE0.08%(max)ND

LIMIT OF ETHYLACETATE0.1%(max)0.05%

PHYSICAL CONTROL

DESCRIPTIONWhite crystalline powderComplies

WATER0.3%(max)0.25%

HEAVY METAL0.001%(max)Complies

RESIDUE ON IGNITION0.1%(max)0.06%

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