Quick Details:

Name: Lovastatin

CAS NO: 75330-75-5

MF: C24H36O5 

MW: 404.55

Appearance: white powder
Standard:USP

Package:25kg/drum
Storage: shading, sealed.

Use: it is mainly used for the treatment of hypercholesterolemia and mixed hyperlipidemia

Description:

Lovastatin (Merck's Mevacor) is a statin drug, used for lowering cholesterol (hypolipidemic agent) in those with hypercholesterolemia to reduce risk of cardiovascular disease. Lovastatin is a naturally occurring compound found in food such as oyster mushrooms, red yeast rice,and Pu-erh.

Specification:

Test Items		Standard	Result
Description		A white to off-white, crystalline powder	Conforms
Identification		IR/UV	Conforms
Specific optical rotation		+324°- +338°	+326.8°
Loss on drying		≤0.3%	0.10%
Sulphated ash		≤0.2%	0.03%
Heavy metals		≤20ppm	＜20ppm
Related compound A		≤0.5%	0.24%
Assay(HPLC)		98.5%-101.0%	99.5%
HPLC Purity	RRT0.66	≤0.15%	0.06%
	RRT0.92	≤0.15%	0.09%
	RRT1.49	≤0.15%	0.14%
	RRT2.43	≤0.15%	0.15%
	Max unknown impurity	≤0.10%	0.08%
	Total impurity	≤1.0%	0.66%
Residual solvents	Ethanol	≤5000ppm	410ppm
	Butyl Acetate	≤5000ppm	120ppm
Conclusion		The results conform with USP35 standard

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