Best Raloxifene HCL, Reliable Raloxifene HCL, Anti Estrogen Steroids Raloxifene hydrochloride (82640-04-8)

Raloxifene HCL General Information

Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of raloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (agonism) and and the blockade of estrogenic pathways in other tissues (antagonism).

Evista is specifically approved for the treatment and prevention of osteoporosis in postmenopausal women, the reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and the reduction in risk of invasive breast cancer in postmenopausal women at high risk of invasive breast cancer. Evista is supplied as a 60 mg tablet designed for oral administration. The recommended initial dose of the drug is one 60 mg tablet daily, which may be administered any time of day without regard to meals.

Raloxifene HCL Use in Cancer

Raloxifene hydrochloride is approved to prevent:
Breast cancer. It is used to decrease the chance of invasive breast cancer in postmenopausal women who have a high risk for developing the disease or who have osteoporosis.
Raloxifene hydrochloride is also approved to prevent and treat:
Osteoporosis in postmenopausal women.
Raloxifene hydrochloride is also being studied in the treatment of other types of cancer.

Raloxifene HCL Mechanism of Action

Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of raloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (agonism) and and the blockade of estrogenic pathways in other tissues (antagonism). The agonistic or antagonistic activity of raloxiffene depends on the extent of recruitment of coactivators and corepressors to estrogen receptor (ER) target gene promotors. Raloxifene appears to act as an estrogen agonist in bone. It decreases bone resorption and bone turnover, increases bone mineral density and decreases fracture incidence

Pure Raloxifene HCL

Product name: Raloxifene hydrochloride
Other name: Raloxifene HCL; KEOXIFENE; AKOS 92138
CAS register number: 82640-04-8
Appearance : Light yellow powder
Molecular formula: C28H28ClNO4S
Molecular weight : 510.04
Melting point : 250-253°C
Assay : 99%
Brand : NJBNsteroid
Manufacturer : Nanjing Bangnuo Biotechnology Co., Ltd
Usage: It is used in the prevention of osteoporosis in postmenopausal women
Storage : Shading, confined preservation

Anti estrogen steroids

Raloxifene hydrochloride(82640-04-8)
Tamoxifen Citrate (54965-24-1)
Anastrozole (Arimidex) CAS120511-73-1
Clomiphene citrate CAS50-41-9
Estradiol CAS50-28-2
Exemestane(Aromasin) CAS107868-30-4
Letrazole(Femara) CAS112809-51-5
Methoxydienone CAS2322-77-2
Norgestrel CAS6533-00-2
Tamoxifen Citrate (Nolvadex) CAS54965-24-1

About the manufacture

Nanjing Bangnuo Biotechnology Co., Ltd. Is a comprehensive and high-tech enterprise specializing in phaarmaceutical raw materials and its intermediates , which including:

Raw steroid powders: Testosterone, Boldenone, Nandrolone, Trenbolone, DECA, Anavar/Oxandrolone, NPP, EQ, Winstrol, Dianabol, Nolvadex, Sildenafil citrate, Cialis, Tadalafil,

Injection steroid liquid: Dianabol 50, Winstrol 100, Anadrol 50, Deca 200, Masteron, Drostanolone Enanthate, TMT Blend 375, Rippex 225 etc.

Peptides: MT-2, GHRP-2, PT-141, CJC-1295, HGH176-191,

SARMs: MK-2866, MK-677, LGD-4033, GW-501516, S4,

Local anesthetics: Benzocaine, Lidocaine, Tetracaine, GBL, Phenacetin, BB, BA etc.

Weight loss drugs: L(-)-Carnitine, Rimonabant, Synephrine, LORCASERIN, Orlistat, Calcium pyruvate, Hydroxycitric acid, Garcinia cambogia, Lotus Leaf Extract, 5-Hydroxytryptophan

With the era of time, now we have developed as integrating R& D, manufacturing, operating and marketing into an organic whole.

We have been serving in this field for over 16 years. Our products achieve the advanced standard of domestic market, many of which conform to the international standard, Kosher Certificate and ISO9001. Our products aimed at global markets , such as United State(USA) , United Kingdom(UK) , Australia , Canada , Spain , France , Germany , Russia , Brasil(Brazil) , Ukraine , South Africa , Norway , Poland , Netherlands(Holland) , Slovakia , Georgia , New Zealand , Sweden etc.

Our factory located in China mainland Nanjing City of Jiangsu Province, which covers an area of 20000 square meters with clean environment and nice layout for the produce of pharmaceutical & its intermediates. We own several large-sized, medium-sized workshops and QA and research center with advanced equipments.

Our company engaged in gym training , and all of our staff will pursue high quality and perfect brand with untiring efforts, and inherit company spirit on "energy-saving, factual, enterprising and innovative ", follow the company management theory of "lives, services or soul of quality ", with the first-class products and high-quality service to meet market's demands.

Old brand, Reliable manufacture, Pure steroids, Competive price, Safe delivery, Best service, We are always here!