Description/ Specification of (S)-Ginsenoside RG3
Product Name: 3-O-[β-D-glucopyranosyl-(1→2)- β
- D-glucopyranosyl]-dammar-24-ene-3β,12β,20S-triol
Product Number: G016013
CAS Number: 14197-60-5
Formula (Hill method): C42H72O13
Formula Weight: 785.01 AMU
Purity(HPLC): ≥ 97.70 %
Price(USD) & Stock: / In Stock
Minimum Purchase: 20mg
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Solubility:
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10 mg/ml in DMSO
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Mechanisms:
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Pathways: Others; Target: Others
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Biological Activity:
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Ginsenoside Rg3 is a steroid glycoside derivative which affects endothelium relaxation in the aorta.
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IC50 Value & Target:
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Others
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ginsenoside Rg3 is one of the main active components responsible for ginseng actions. Ginsenoside Rg3 was the most potent fraction of ginseng saponins and a more marked inhibitor of IBa2+ than is ginsenoside Rf. ginsenoside Rg3 as a new active component is well consistent with results of the previous study which examined the effects of ginsenosides on neuroprotection in cultured cortical cells (Kim et al., 1998). They found ginsenoside Rg3 to be one of the major active components for inhibiting glutamate-induced neuronal cell death and Ca2+ influx through glutamate receptors [1].
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References:
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[1]. Rhim, H., et al., Ginseng and ginsenoside Rg3, a newly identified active ingredient of ginseng, modulate Ca2+ channel currents in rat sensory neurons. Eur J Pharmacol, 2002. 436(3): p. 151-8.
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