Best Flumazenil Powder, Active Pharmaceutical Ingredients Flumazenil (Romazicon) CAS 78755-81-4

----Flumazenil Half life----

Initial distribution half-life is 4 to 11 minutes and the terminal half-life is 40 to 80 minutes. Prolongation of the half-life to 1.3 hours in patients with moderate hepatic impairment and 2.4 hours in severely impaired patients. Compared to adults, the elimination half-life in pediatric patients was more variable, averaging 40 minutes (range: 20 to 75 minutes).

----Flumazenil Functions----

1. Flumazenil is of benefit in patients who become excessively drowsy after benzodiazepines are used for either diagnostic or therapeutic procedures.
2. It has been used as an antidote in the treatment of benzodiazepine overdoses It reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine binding site on the GABAA receptor. There are many complications that must be taken into consideration when used in theacute care setting.
3. It has also been used in hepatic encephalopathy, though results have been mixed

----Pure Flumazenil----

Product name	Flumazenil (Romazicon)
Synonyms	Anexate, Flumazenilo, Flumazenilum, Flumazepil, Lanexat
CAS NO.	78755-81-4
Category	Active Pharmaceutical Ingredients
MF	C15H14FN3O3
MW	303.29
Melting point	201-203o C
Water solubility	128MG/L
Presentation	White crystalline powder
Content	99.0%MIN
Loss On Drying	≤ 5%
Sulphated Ash	≤ 5%
Heavy Metals	≤ 10PPM
Total microbacterial count	NMT 1000cfu/g
Salmonella	NMT100cfu/g
Package	1kg/ foil bag or as you wish
Storage	Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Shelf Life	Two years when properly stored
Brand	NJBNsteroid
Manufacture	Nanjing Bangnuo Biotechnology Co., Ltd

About the Flumazenil manufacture

Nanjing Bangnuo Biotechnology Co., Ltd. Is a comprehensive and high-tech enterprise specializing in phaarmaceutical raw materials and its intermediates , which including:

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We have been serving in this field for over 16 years. Our products achieve the advanced standard of domestic market, many of which conform to the international standard, Kosher Certificate and ISO9001. Our products aimed at global markets , such as United State(USA) , United Kingdom(UK) , Australia , Canada , Spain , France , Germany , Russia , Brasil(Brazil) , Ukraine , South Africa , Norway , Poland , Netherlands(Holland) , Slovakia , Georgia , New Zealand , Sweden etc.

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