Orlistat Weight loss Medicine CAS: 96829-58-2 99%
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Basic info:

Product Name: Orlistat
Synonyms: (S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S, 3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER; RO-18-0647; (-)-TETRAHYDROLIPSTATIN; ORLISTAT; N-FORMYL-L-LEUCINE (1S)-1-[[(2S, 3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]DODECYL ESTER; XENICAL; (-)-Tetrahydrolipstatin(EquivalentToOrlistat); Orlipastat
CAS: 96829-58-2
MF: C29H53NO5
MW: 495.73
Chemical Properties: Off-White Solid
Usage: An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent.
Usage: antidiabetic
Usage: Orlistat is an antiobesity agent. Orlistat is an pancreatic lipase inhibitor.
Usage: Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity.

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Orlistat:

Orlistat is a drug designed to treat obesity. It is marketed as a prescription drug under the trade name Xenical by Roche in most countries, and is sold over-the-counter as Alli by GlaxoSmithKline in the United Kingdom and the United States. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
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Orlistat:
Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.

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Orlistat:
The effectiveness of orlistat in promoting weight loss is definite but modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2–3 kilograms (4.4–6.6 lb) more than those not taking the drug over the course of a year. Orlistat also modestly reduces blood pressure and appears to prevent the onset of type 2 diabetes, whether from the weight loss itself or to other effects. In a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.

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Orlistat:
Benefits aside, however, orlistat is notorious for its gastrointestinal side effects (sometimes referred to as treatment effects), which can include steatorrhea (oily, loose stools). They decrease with time, however, and are the most frequently reported adverse effects of the drug. In the United States and the European Union, orlistat is available for sale without a prescription. Over-the-counter approval was controversial in the United States, with consumer advocacy group Public Citizen repeatedly opposing it on safety and efficacy grounds. Generic formulations of orlistat are available in some countries. In Australia it is listed as an S3 medication and so is available over the counter in pharmacies.
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Weight loss Medicine

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Orlistat CAS: 96829-58-2
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About us:
Our company is a comprehensive and high-tech enterprise specializing in pharmaceutical raw materials ,

We have been serving in this field for over 16 years. Our products achieve the advanced standard of domestic market, many of which conform to the international standard, Kosher Certificate and ISO9001. Our products aimed at global markets , such as United State(USA) , United Kingdom(UK) , Australia , Canada , Spain , France , Germany , Russia , Brasil(Brazil) , Ukraine , South Africa , Norway , Poland , Netherlands(Holland) , Slovakia , Georgia , New Zealand , Sweden etc.

Our factory located in China mainland wuhan City of hubei Province, which covers an area of 20000 square meters with clean environment and nice layout for the produce of pharmaceutical & its intermediates. We own several large-sized, medium-sized workshops and QA and research center with advanced equipments.

Our company engaged in gym training , and all of our staff will pursue high quality and perfect brand with untiring efforts, and inherit company spirit on "energy-saving, factual, enterprising and innovative ", follow the company management theory of "lives, services or soul of quality ", with the first-class products and high-quality service to meet market's demands.

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