| Purity: | 99% |
|---|---|
| Model Number: | 638-94-8 |
| Brand Name: | NJBN STEROID |
| Grade Standard: | Medicine Grade |
| Type: | Antifungal |
| Place of Origin: | China (Mainland) |
| EINECS No.: | 211-351-6 |
| MF: | C24H32O6 |
| Other Names: | Desonide |
| CAS No.: | 638-94-8 |
| Sample: | Free |
| Market: | Worldwide |
Quick Details
Specifications
Desonide 638-94-8 Pharmaceutical Raw Materials For Antifungal
_________________________________________________________________________________________
Desonide
|
Product Name |
Desonide |
|
CAS |
638-94-8 |
|
MF |
C24H32O6 |
|
MW |
416.51 |
|
Purity |
99% |
|
EINECS |
211-351-6 |
|
Appearance |
Off-White Solid |
|
Categories |
Chiral Reagents; Intermediates & Fine Chemicals; Pharmaceuticals; Steroids; SPORANOX; Hormone Drugs |
|
Synonyms |
d-2083; steroderm; PREDNACINOLONE; DESONIDE |
|
Usage |
antifungal , Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490). |
_________________________________________________________________________________________
Description OF Desonides
Desonides is the generic name of a low-potency topical corticosteroid that has been available Since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children. It has a fairly good safety profile And is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam.
_________________________________________________________________________________________
COA
|
Items of analysis |
Specification |
Results |
|
Description |
white or off-white crystalline powder |
white crystalline powder |
|
Identification |
A: uv B: HPLC |
complies |
|
Melting point |
265°C ～275°C |
265°C ～270°C |
|
Solubility |
water: practically insoluble / ethanol: slightly soluble |
complies |
|
Specificoptical rotation: |
+103°～+ 111° |
+ 106° |
|
Loss on drying |
≤ 0.5% |
0.13% |
|
Sulfated ash |
≤0.1% |
0.02% |
|
Heavy metal |
≤20ppm |
complies |
|
max impurity |
≤1.0% |
0.66% |
|
total impurities |
≤2.0% |
1.6% |
|
Assay(HPLC) |
97.0%～103.0% |
99.2% |
|
Dichloromethane |
not more than 600ppm |
complies |
|
Methanol |
not more than 3000ppm |
complies |
|
Pyridine |
not more than 200ppm |
complies |
|
Acetone |
not more than 5000ppm |
complies |
|
Particle size |
99% ≤ 30 microns |
complies |
|
Conclusion |
Qualified |
|
_________________________________________________________________________________________
Use OF Desonides
(1) Desonides belongs to the group of medications known as topical corticosteroids. It is used to Treat various skin conditions, including rashes. It works by reducing inflammation and itching. Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.
(2) Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
(3) After applying the medication, wash and dry your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma, or cause irritation. Also, avoid getting this medication in the nose or mouth. If you get this medication in your eyes, nose, or mouth, rinse immediately with plenty of water.