Phenacetin 62-44-2 For Analgesic And Antipyretic 99%

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Phenacetin

Synonyms: 1-ACETYL-P-PHENETIDIN; 4-ACETOPHENETIDIDE; 4-acetophenetidine; 4'-ETHOXYACETANILIDE; 4-ETHOXYACETANILIDE; ACETOPHENETIDIN; ACETOPHENETIDINE; ACET-P-PHENETIDINE

CAS: 62-44-2

MF: C10H13NO2

MW: 179.22

Assay: 99%

EINECS: 200-533-0

Appearance : white crystalline powder

Usage : 1. Analgesic, antipyretic. 2. Glycosylation inhibitor

Categories: Organics; Amines; Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals; Other APIs

Stability: Stable. Incompatible with strong oxidizing agents, strong acids.

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Description

The antipyretic and analgesic effects of phenacetin are similar to that of acetylsalicylic acid, which is mainly used as anti-inflammatory drugs with a slow and long-lasting effect. It is an effective drug on the treatment of headache, neuralgia, joint pain and fever.

However, it has a weak effect on treating anti-rheumatic, anti-inflammatory. Overdose can cause methemoglobinemia, resulting in hypoxia. Long-term medication can damage the kidneys, and even cause papillary necrosis, thus it should be taken with caution.

It is often combined with aspirin, caffeine, for making aspirin compound (0.162 g of non-phenacetin, 0.227 g of aspirin, and 0.035 g of caffeine) for the treatment of colds with a small toxicity. Further addition of a small amount of the chlorpheniramine can produce chlorpheniramine cold tablets which can be applied to the treatment of colds, headache, neuralgia, rheumatism and so on.

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Phenacetin COA

Product Name	Phenacetin
Quantity	500KG	Standard		BP 68 edition
Test Items	Specification		Test Results
Description	Should comply with the standard		Pass
Identification	Should be positive reaction		Pass
P-Phenetidine	Brownish red 4#		Pass
4-chloroacetanilide	Should comply with standard		Pass
Sulphated ash	≤0.1%		0.06%
Melting point	134℃ to 137℃		134℃ to 137℃
Appearance	≥99%		100.58%
Conclusion	Complies with BP68 edition

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Application

1. Used for organic synthesis of raw materials and drug intermediates from acetaminophen ether.

2. Antipyretic analgesics for the treatment of fever, headache, neuralgia.

3. Active pharmaceutical ingredient for Scientific Research.