Pralmorelin 158861-67-7 Growth Hormone Peptides 98%

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Pralmorelin

Product name	Pralmorelin
Synonyms	(DES-ALA3)-GROWTH HORMONE-RELEASING PEPTIDE-2; (DES-ALA3)-KP-102; GHRP-2
CAS NO	158861-67-7
purity	98%
MF	C42H50N8O5
MW	746.91
Appearance	White Powder
Categories	Peptide , Peptides
Usage	lean body mass and reduce adiposity, also has a protective effect on the liver and an anti-inflammatory effect.
Synonyms	PRALMORELIN; D-ALA-D-NAL(2)-ALA-TRP-D-PHE-LYS-NH2 ACETATE SALT; D-ALA-BETA-(2-NAPHTHYL)-D-ALA-TRP-D-PHE-LYS AMIDE; D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2; (DES-ALA3, D-ALA1, D-2-NAL2)-GHRP-6; (DES-ALA3)-GHRP-2; (DES-ALA3)-GROWTH HORMONE-RELEASING PEPTIDE-2; (DES-ALA3)-KP-102

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Description of Pralmorelin

GHRP-2 is synergistic with GHRH due to secondary actions on hypothalamic neurons. The quantity of GH released by a living mammal to which GHRP-2 and GHRH are administered exceeds the combined release of each compound when measured when taken alone.

In humans, a dose of 1mcg/kg (100mg for a 100kg male) of GHRP-2 when combined with a GHRH of equal dosage creates a three-hour pulse of GH that is double the amplitude of an 8 IU synthetic (e. Coli derived) growth hormone dose. IV, intramuscular and subcutaneous routes lead to different onset times but roughly similar peaks and declines.

GHRP-2 is a synthetic ghrelin analogue. Like ghrelin, it stimulates release of endogenous growth hormone from somatotropes in the anterior pituitary; also like ghrelin, it is synergistic with endogenous growth hormone releasing-hormone (GHRH) as well as with synthetic GHRH analogues such as Sermorelin or GRF(1-29). Whereas GHRP-2 and other ghrelin analogues increase the number of somatotropes involved in the GH pulse by inhibiting somatostatin, GHRH increases the pulse amplitude per pituitary cell or somatotrope by other means. Unlike ghrelin, GHRP-2 is not lipogenic meaning it does not induce fat storage. While ghrelin has a very important role in hunger, GHRP-2 as an analog of ghrelin does not increase appetite significantly. GHRP-2 is synergistic with GHRH due to secondary actions on hypothalamic neurons. The quantity of GH released by a living mammal to which GHRP-2 and GHRH are administered exceeds the combined release of each compound when measured when taken alone.

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COA

Product Name	GHRP-2 Acetate
Sequence	D-Ala-D-B-Nal-Trp-D-Phe-Lys-NH2
Cas No.	158861-67-7
Molecular Formula	C45H55N9O6
Molecular Weight	818.0
Purity (HPLC)	98.0%min.
Appearance	White powder
Single Impurity (HPLC)	1.0%max
Amino Acid Composition	±10% of theoretical
Peptide Content (N%)	≥80.0%
Water Content(Karl Fischer)	≤6.0%
Acetate Content (HPIC)	≤12.0%
MS(ESI)	Consistent
Mass Balance	95.0~105.0%

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Application of Pralmorelin

GHRP-2 basically acts exactly like ghrelin. It can induce food consumption just like ghrelin and stimulate GH secretion. When it be infused, GHRP-2 makes the GH levels in the body increase a lot , and, it can induce cell AMP secretion the way that GRF tends to.

Aside from that, the supplements of GHRP-2 are known to be anti-inflammatory. However, its results tend to differ between research test subjects, depending on how each subject's pituitary somatotrophs choose to respond based on the different receptor subtypes of GHRP overall.