Parkinsonian Treatment Drug Pramipexole 104632-26-0 98%

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Pramipexole

Synonyms: (s)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole; n'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine; pramipexol; (S)-2-Amino-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazoltetrahydrobenzothiazol; pramipexole; pramipexolole dihydrochloride; Pramipexol diclorohidrato monohidrato; pramipexole 2hcl monohydrate

CAS: 104632-26-0

MF: C10H17N3S

MW: 211.33

Purity : 98%

Appearance: White Powder

Categories: All Inhibitors; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Chiral Reagents; Sulfur & Selenium Compounds; API; Mirapexin, Sifrol

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Product description

1. Pramipexole is a dopamine agonist belonging to the same class of drugs as Cabergoline. Along with treating Parkinson's, Pramipexole is also prescribed for the treatment of restless legs syndrome. The drug has also shown promising signs in the treatment of bipolar depression, although it has never officially held this label.

2. Pramipexole is a dopamine agonist that directly correlates with the prolactin hormone. As dopamine levels in the body go up, prolactin levels go down. It does this by having a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor its affinity for the D3 receptor is seven times greater than any existing dopamine agonist.

3. The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why it's used to treat Parkinson's disease and in some cases Alzheimer's disease. Through acting on the D3 receptor, Pramipexole also affects a man's sexual interest and activity. Prolactin is in part directly responsible for a man's refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently.

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