Product Main

Quick Details

Purity: 99%
Model Number: 148553-50-8
Brand Name: NJBN STEROID
Grade Standard: Medicine Grade
Type: Neuropathic Pain
Place of Origin: China (Mainland)
EINECS No.: 200-659-6
MF: C8H17NO2
Other Names: Pregabalin
CAS No.: 148553-50-8
Sample: Free
Market: Worldwide

Specifications

Pregabalin A New Antiepileptic DrugsCAS 148553-50-8Off-White Solid99%

_______________________________________________________________________________________


Pregabalin

CAS: 148553-50-8

MF: C8H17NO2

MW: 159.23

EINECS: 200-659-6

Purity : 99%

Appearance: Off-White Solid

Usage: New antiepileptic drugs , Active pharmaceutical ingredients

Synonyms: 3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID; (3S)-3-(AMINOM

ETHYL)-5-METHYLHEXANOIC ACID; PREGABALIN; Pregablin; 3-(Aminomethyl)

-5-methyl-hexanoic acid; PREDNISOLONESODIUMPHOSPHATE; (R)-Pregaba

lin; (S)-Pregabalin

Categories: APIs; Miscellaneous Biochemicals; Intermediates & Fine Chemicals; Neurochemicals; Pharmaceuticals; API; Pfizer compounds; LYRICA

_______________________________________________________________________________________


Product description
:

Pregabalin is a new antiepileptic drug, antiepileptic drugs and therapeutic drugs for neuropathic pain, having a γ-amino butyric acid structure on its molecular structure, which has anticonvulsant effects, and is successfully developed by the company Pfizer for the treatment of peripheral neuropathic pain, or adjuvant treatment of partial seizures.

Neuropathic pain is one of the most difficult chronic pain syndromes to treat , dull pain, burning, tingling as the main feature, there are a lot of incentives of neuralgia, diabetes, infections (such as herpes zoster), cancer and AIDS, etc. Can cause neurological pain, in Europe about 3% of the population suffer from neuralgia torture.


_______________________________________________________________________________________

COA

Items of analysis

Specification

Results

Appearance

White or almost white powder

conforms

Identification

IRandHPLC

conforms

Loss on drying

≤0.5%

0.2%

Specific Rotation

+10°~+12°

+10.77°

Residue on ignition

≤0.1%

0.08%

Heavy metals

≤20ppm

conforms

impurity C

≤0.1%

conforms

Any impurity

≤0.1%

0.044%

Total impurity

≤1.0%

0.14%

Assay(HPLC)

98%-101%

99.6%

R-isomer

≤0.15%

0.033%

Bromide cintent(Titrmetry)

≤500ppm

26ppm

Ethanol

≤5000ppm

conforms

Isopropyl alcohol

≤5000ppm

142ppm

Ethyl Acetate

≤5000ppm

conforms

Chloroform

≤60ppm

conforms

Conclusion

Qualified



_______________________________________________________________________________________

Product Application

1. S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.

2. Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin.


_______________________________________________________________________________________


The Main Product List:

Clarithromycin

CAS: 81103-11-9

Folic acid

CAS: 59-30-3

Itraconazole

CAS: 84625-61-6

Daunorubicin hydrochloride

CAS: 23541-50-6

Levamisole hydrochloride

CAS: 16595-80-5

Ketoconazole

CAS: 65277-42-1

Tacrolimus

CAS: 104987-11-3

Trilostane

CAS: 13647-35-3

Rapamycin

CAS: 53123-88-9

PF-2341066/Crizotinib

CAS: 877399-52-5

Everolimus

CAS: 159351-69-6

Zoledronic acid

CAS: 118072-93-8

Aminoglutethimide (Cytadren)

CAS: 125-84-8

Rasagiline mesylate

CAS: 161735-79-1

Clopidogrel hydrogen sulfate

CAS: 135046-48-9

Doxepin hydrochloride

CAS: 1229-29-4

Naphazoline hydrochloride

CAS: 550-99-2

TELMISARTAN

CAS: 144701-48-4

Pramipexole

CAS: 104632-26-0

Furazabol

CAS: 1239-29-8