Purity: | 99% |
---|---|
Model Number: | 148553-50-8 |
Brand Name: | NJBN STEROID |
Grade Standard: | Medicine Grade |
Type: | Neuropathic Pain |
Place of Origin: | China (Mainland) |
EINECS No.: | 200-659-6 |
MF: | C8H17NO2 |
Other Names: | Pregabalin |
CAS No.: | 148553-50-8 |
Sample: | Free |
Market: | Worldwide |
Quick Details
Specifications
Pregabalin A New Antiepileptic DrugsCAS 148553-50-8Off-White Solid99%
_______________________________________________________________________________________
Pregabalin
CAS: 148553-50-8
MF: C8H17NO2
MW: 159.23
EINECS: 200-659-6
Purity : 99%
Appearance: Off-White Solid
Usage: New antiepileptic drugs , Active pharmaceutical ingredients
Synonyms: 3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID; (3S)-3-(AMINOM
ETHYL)-5-METHYLHEXANOIC ACID; PREGABALIN; Pregablin; 3-(Aminomethyl)
-5-methyl-hexanoic acid; PREDNISOLONESODIUMPHOSPHATE; (R)-Pregaba
lin; (S)-Pregabalin
Categories: APIs; Miscellaneous Biochemicals; Intermediates & Fine Chemicals; Neurochemicals; Pharmaceuticals; API; Pfizer compounds; LYRICA
_______________________________________________________________________________________
Product description:
Pregabalin is a new antiepileptic drug, antiepileptic drugs and therapeutic drugs for neuropathic pain, having a γ-amino butyric acid structure on its molecular structure, which has anticonvulsant effects, and is successfully developed by the company Pfizer for the treatment of peripheral neuropathic pain, or adjuvant treatment of partial seizures.
Neuropathic pain is one of the most difficult chronic pain syndromes to treat , dull pain, burning, tingling as the main feature, there are a lot of incentives of neuralgia, diabetes, infections (such as herpes zoster), cancer and AIDS, etc. Can cause neurological pain, in Europe about 3% of the population suffer from neuralgia torture.
_______________________________________________________________________________________
COA
Items of analysis |
Specification |
Results |
Appearance |
White or almost white powder |
conforms |
Identification |
IRandHPLC |
conforms |
Loss on drying |
≤0.5% |
0.2% |
Specific Rotation |
+10°~+12° |
+10.77° |
Residue on ignition |
≤0.1% |
0.08% |
Heavy metals |
≤20ppm |
conforms |
impurity C |
≤0.1% |
conforms |
Any impurity |
≤0.1% |
0.044% |
Total impurity |
≤1.0% |
0.14% |
Assay(HPLC) |
98%-101% |
99.6% |
R-isomer |
≤0.15% |
0.033% |
Bromide cintent(Titrmetry) |
≤500ppm |
26ppm |
Ethanol |
≤5000ppm |
conforms |
Isopropyl alcohol |
≤5000ppm |
142ppm |
Ethyl Acetate |
≤5000ppm |
conforms |
Chloroform |
≤60ppm |
conforms |
Conclusion |
Qualified |
_______________________________________________________________________________________
Product Application
1. S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.
2. Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin.
_______________________________________________________________________________________
The Main Product List:
Clarithromycin |
CAS: 81103-11-9 |
Folic acid |
CAS: 59-30-3 |
Itraconazole |
CAS: 84625-61-6 |
Daunorubicin hydrochloride |
CAS: 23541-50-6 |
Levamisole hydrochloride |
CAS: 16595-80-5 |
Ketoconazole |
CAS: 65277-42-1 |
Tacrolimus |
CAS: 104987-11-3 |
Trilostane |
CAS: 13647-35-3 |
Rapamycin |
CAS: 53123-88-9 |
PF-2341066/Crizotinib |
CAS: 877399-52-5 |
Everolimus |
CAS: 159351-69-6 |
Zoledronic acid |
CAS: 118072-93-8 |
Aminoglutethimide (Cytadren) |
CAS: 125-84-8 |
Rasagiline mesylate |
CAS: 161735-79-1 |
Clopidogrel hydrogen sulfate |
CAS: 135046-48-9 |
Doxepin hydrochloride |
CAS: 1229-29-4 |
Naphazoline hydrochloride |
CAS: 550-99-2 |
TELMISARTAN |
CAS: 144701-48-4 |
Pramipexole |
CAS: 104632-26-0 |
Furazabol |
CAS: 1239-29-8 |