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Purity: 99%
Model Number: 33515-09-2
Brand Name: NJBN STEROID
Grade Standard: Medicine Grade
Type: Auxiliaries and Other Medicinal Chemicals
Place of Origin: China (Mainland)
EINECS No.: 232-895-0
MF: C55H75N17O13
Other Names: Gonadorelin
CAS No.: 33515-09-2
MW: 1182.29

Specifications

Gonadorelin CAS 33515-09-2Gonadotropin-releasing Hormone Peptide



Basic Info:


Product Name

Gonadorelin

CAS

33515-09-2

MF

C55H75N17O13

MW

1182.29

EINECS

232-895-0

Purity

98%

Appearance

white powder

usage

gonadotropin-releasing hormone

Categories

Gonadotropin-releasing hormone (GnRH); Peptide Receptors; peptide

Synonyms

LUTEINIZING HORMONE-RELEASING HORMONE (SEA BREAM);

LUTENIZING HORMONE RELEASING HORMONE HUMAN;

LUTEINIZING HORMONE-RELEASING HORMONE (LAMPREY III);


Desctiprion:


Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary.

GnRH is available as gonadorelin hydrochloride and gonadorelin diacetate tetrahydrate for injectable use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.


Specification :

Item

Specification

Result

Appearance

White powder

Complies

Identification

Positive

Complies

Assay

98.0% min

98.8%

Loss on Drying

8.0%max.

5.8%

Mass Balance

95.0~105.0%

Complies

HCl Content (HPIC)

10.0%max

8.5%

Peptide Content (N%)

80.0%min.

88.0%

Amino Acid Composition

±10% of theoretical

Complies

Single Impurity (HPLC)

0.5%max.

0.45%

Specific Rotation (20/D)

-55.0~-65.0(c=1 1%HAc)

Complies

MS(ESI)

Consistent

Complies


Application:


Gonadorelin is a medicine that is the same as gonadotropin-releasing hormone (GnRH) that is naturally released from the hypothalamus gland.

GnRH causes the pituitary gland to release other hormones (luteinizing hormone [LH] and follicle-stimulating hormone [FSH]). LH and FSH control development in children and fertility in adults.

Gonadorelin is used to test how well the hypothalamus and the pituitary glands are working. It is also used to cause ovulation (release of an egg from the ovary) in women who do not have regular ovulation and menstrual periods because the hypothalamus gland does not release enough GnRH.


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