| Purity: | 98.9%min |
|---|---|
| Model Number: | 25316-40-9 |
| Brand Name: | NJBN |
| Grade Standard: | Medicine Grade |
| Type: | Antineoplastic Agents |
| Place of Origin: | China (Mainland) |
| EINECS No.: | 25316-40-9 |
| MF: | C27H30ClNO11 |
| Other Names: | Doxorubicin Hydrochloride |
| CAS No.: | 25316-40-9 |
| product: | Doxorubicin Hydrochloride |
| type: | APIs of Anti-cancer Drugs |
| MOQ: | 1g |
| Delivery: | Safely & Timely |
| Price: | Affordable |
| Quality: | Reliable |
| Advantage: | Specialized & Experienced |
Quick Details
Specifications
25316-40-9 APIs of Anti-cancer Drugs 98.9%min Doxorubicin Hydrochloride
1. Doxorubicin Hydrochloride Use in Cancer
1) Acute lymphoblastic leukemia (ALL).
2) Acute myeloid leukemia (AML).
3) Breast cancer. It is also used as adjuvant therapy for breast cancer that has spread to the lymph nodes after surgery.
4) Gastric (stomach) cancer.
5) Hodgkin lymphoma.
6) Neuroblastoma.
7) Non-Hodgkin lymphoma.
8) Ovarian cancer.
9) Small cell lung cancer.
10) Soft tissue and bone sarcomas.
11) Thyroid cancer.
12) Transitional cell bladder cancer.
13) Wilms tumor.
2. Doxorubicin Hydrochloride profile
Product name: Doxorubicin Hydrochloride
Alias: (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7
Type: APIs of Anti-cancer Drugs
CAS:25316-40-9
MF: C27H30ClNO11
MW:579.98
EINECS:246-818-3
Assay: 98.9%min
Appearance: Orange-red or red crystalline powder
Usage: Used as an antineoplastic
Package: 1g/5g/10g/100g/1kg
3. Doxorubicin hydrochloride Description
Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently.
4. Doxorubicin Hydrochloride specifications:
Anna Huang: +8617327094661; annahuang@chembj dot com
TAG:
Doxorubicin Hydrochloride
Doxorubicin Hydrochloride liposome
Doxorubicin Hydrochloride adriamycin
Doxorubicin Hydrochloride side effects
Doxorubicin Hydrochloride injection
Doxorubicin Hydrochloride and cyclophosphamide
Doxorubicin Hydrochloride msds
Doxorubicin Hydrochloride drug
Doxorubicin Hydrochloride salt 99
1. Doxorubicin Hydrochloride Use in Cancer
1) Acute lymphoblastic leukemia (ALL).
2) Acute myeloid leukemia (AML).
3) Breast cancer. It is also used as adjuvant therapy for breast cancer that has spread to the lymph nodes after surgery.
4) Gastric (stomach) cancer.
5) Hodgkin lymphoma.
6) Neuroblastoma.
7) Non-Hodgkin lymphoma.
8) Ovarian cancer.
9) Small cell lung cancer.
10) Soft tissue and bone sarcomas.
11) Thyroid cancer.
12) Transitional cell bladder cancer.
13) Wilms tumor.
2. Doxorubicin Hydrochloride profile
Product name: Doxorubicin Hydrochloride
Alias: (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7
Type: APIs of Anti-cancer Drugs
CAS:25316-40-9
MF: C27H30ClNO11
MW:579.98
EINECS:246-818-3
Assay: 98.9%min
Appearance: Orange-red or red crystalline powder
Usage: Used as an antineoplastic
Package: 1g/5g/10g/100g/1kg
|
MOQ |
1g |
|
Payment |
Western Union, Money gram, T/T, Bitcoin |
|
Shipment |
EMS, DHL, Fedex,UPS,TNT. |
|
Port |
HONGKONG, SHENZHNE, SHANGHAI, NANJING |
|
Delivery time |
Safe & Timely, Within 24 hours after confirming the payment |
|
Leading time |
4~6 working days. |
|
Brand |
NJBN |
|
Manufacture |
Yes (Nanjing Bangnuo Biotechnology Co., Ltd.) |
|
COA |
Yes |
|
Price |
Affordable |
|
Advantage |
Specialized & Experienced |
|
Market |
Global distribution |
3. Doxorubicin hydrochloride Description
Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently.
4. Doxorubicin Hydrochloride specifications:
|
TEST |
SPECIFICATION |
RESULT |
|
Appearance |
Orange-red or red crystalline powder; No visible evidence of contamination by foreign matter. |
Conforms |
|
Solubility |
Soluble in water and methanol; slightly soluble in ethanol; practically insoluble in acetone. |
Conforms |
|
Identification A |
IR spectrum corresponds to the IR spectrum of the reference standard |
Conforms |
|
Identification B |
The retention time of the doxorubicin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. |
Conforms |
|
pH |
4.0 to 5.5 |
5.1 |
|
Water Content |
Not More Than 4.0% |
0.8% |
|
Related Substances |
||
|
Impurity A (Doxorubicinone) |
Not More Than 0.5% |
0.1% |
|
Any Other unknown Impurity |
Not More Than 0.1% |
0.07% |
|
Total unknown Impurities |
Not More Than 0.3% |
0.2% |
|
Total Impurities |
Not More Than 1.0% |
0.9% |
|
Assay |
98.0% to 102.0% of C27H30ClNO11 calculated on the anhydrous, solvent-free basis |
98.9% |
|
Residual Solvents |
||
|
Acetone |
Not More Than 0.5% |
0.31% |
|
Acetone +Ethanol |
Not More Than 2.5% |
0.60% |
|
methanol |
Not More Than 0.3% |
Not detected |
|
Dichloromethane |
Not More Than 0.06% |
Not detected |
|
Conclusion |
To be complied with USP 31 specifications |
|
Anna Huang: +8617327094661; annahuang@chembj dot com
TAG:
Doxorubicin Hydrochloride
Doxorubicin Hydrochloride liposome
Doxorubicin Hydrochloride adriamycin
Doxorubicin Hydrochloride side effects
Doxorubicin Hydrochloride injection
Doxorubicin Hydrochloride and cyclophosphamide
Doxorubicin Hydrochloride msds
Doxorubicin Hydrochloride drug
Doxorubicin Hydrochloride salt 99