Factory Direct Terbinafine Hydrochloride 78628-80-5 for Antifungal

Product Name: Terbinafine Hydrochloride 
Synonyms: (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethylaminehydroc;lamosil;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmon;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmonohydrochloride;TERBINAFINE HCL;N-[(2E)-6,6-DIMETHYL-2-HEPTEN-4-YNYL]-N-METHYL-1-NAPHTHALENEMETHANAMINE;TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE;(e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine monohydrochloride 
CAS: 78628-80-5 
MF: C21H26ClN 
MW: 327.89 
EINECS: 245-385-8 
Chemical Properties Crystalline Powder 
Usage An orally active, antimycotic allylamine related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal. 

Medical uses

Terbinafine is mainly effective on the dermatophyte group of fungi.

as a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals.

Oral 250-mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. the tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied. In 2009, results from a clinical study of a new formulation (terbinafine in transfersomes, referred to as TDT-067) for topical treatment of onychomycosis were reported by Celtic Pharma.

Terbinafine hydrochloride may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.


Hot selling pharmaceutical raw materials

Clarithromycin  CAS: 81103-11-9 
PF-2341066/Crizotinib CAS: 877399-52-5
Rapamycin CAS: 53123-88-9 
Trilostane  CAS: 13647-35-3
Tacrolimus  CAS: 104987-11-3 
Ketoconazole CAS: 65277-42-1 
Levamisole hydrochloride  CAS: 16595-80-5 
Daunorubicin hydrochloride  CAS: 23541-50-6
Folic acid  CAS: 59-30-3 
Itraconazole  CAS: 84625-61-6
Everolimus  CAS: 159351-69-6
Zoledronic acid  CAS: 118072-93-8 
Aminoglutethimide (Cytadren) CAS: 125-84-8
Rasagiline mesylate  CAS: 161735-79-1 
Clopidogrel hydrogen sulfate  CAS: 135046-48-9
Doxepin hydrochloride  CAS: 1229-29-4 
Naphazoline hydrochloride  CAS: 550-99-2 
TELMISARTAN  CAS: 144701-48-4
Pramipexole  CAS: 104632-26-0 
Furazabol CAS: 1239-29-8 
Triamcinolone acetonide  CAS: 76-25-5 
Etilefrine hydrochloride  CAS: 943-17-9 
Promethazine hydrochloride CAS: 58-33-3 
O-PHOSPHORYLETHANOLAMINE CAS: 1071-23-4
Cilastatin   CAS: 82009-34-5 
Lovastatin  CAS: 75330-75-5
Erythromycin  CAS: 114-07-8