| Purity: | 99 |
|---|---|
| Model Number: | 90098-04-7 |
| Brand Name: | NJBN STEROID |
| Grade Standard: | Medicine Grade |
| Type: | Vitamins, Amino Acids and Coenzymes |
| Place of Origin: | China (Mainland) |
| EINECS No.: | 90098-04-7 |
| MF: | C19H15ClN2O4 |
| Other Names: | Rebamipide |
| CAS No.: | 90098-04-7 |
| Sample: | Free |
| Market: | Worldwide |
Quick Details
Specifications
Product Name: Rebamipide
Synonyms: (+-)-1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoica;(+-)-2-(4-chlorobenzoylamino)-3-(2(1h)-quinolinon-4-yl)propionicacid;1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoicaci(;2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-(+-)-4-quinolinepropanoicaci;opc12759;opc-12759;Rebamipid;REBAMIPIDE
CAS: 90098-04-7
MF: C19H15ClN2O4
MW: 370.79
Uses It is used for treating stomach ulcers.
It is a kind of novel anti-ulcer drugs.
COA
|
Items of analysis |
Specification |
Results |
|
Character |
A white crystalline powder, N, dissolved N- two methyl amide, |
Compliance |
|
Identification |
Should comply with the provisions |
Compliance |
|
Chlorides |
≤0.04% |
Compliance |
|
Related substances |
≤0.5% |
0.1% |
|
Acetone |
≤0.5% |
0.006% |
|
Methanol |
≤0.5% |
0.009% |
|
Ethanol |
≤0.5% |
Not detected |
|
Dichloromethane |
≤0.006% |
Not detected |
|
Acetic acid |
≤0.5% |
Not detected |
|
Dry weight loss |
≤2.0% |
0.92% |
|
Residue on ignition |
≤0.1% |
0.08% |
|
Heavy metals |
≤0.001% |
Compliance |
|
Assay |
≥99% |
99.6% |
|
Conclusion |
Qualified |
|
Application
It is effective in prevention of ulcers and promoting ulcer healing. Studies have shown that it is effective against various experimental gastric ulcers and can promote gastric prostaglandin production, protect the gastric mucosa from the damage of various hazards ulcerogenic factors. It is suitable in the treatment of gastric ulcer, acute gastritis, the chronic gastritis in acute exacerbation stage, and stomach mucosal lesions. Therefore, it has relative high clinical value.
With the wild application of proton pump inhibitor (PPI), and the primary approach of treatment of gastric ulcer being the eradication of Helicobacter pylori infection, the clinical healing rate of peptic ulcer can be as high as 80% to 90%. However, the problem of the recurrence of ulcer recurrence still remains to be resolved. In recent years, the relationship between the quality of ulcer healing and ulcer recurrence has attracted more and more attention.

