| Purity: | 99 |
|---|---|
| Model Number: | 13647-35-3 |
| Brand Name: | NJBN STEROID |
| Grade Standard: | Medicine Grade |
| Type: | Vitamins, Amino Acids and Coenzymes |
| Place of Origin: | China (Mainland) |
| EINECS No.: | 237-133-0 |
| MF: | C20H27NO3 |
| Other Names: | Trilostane |
| CAS No.: | 13647-35-3 |
| Sample: | Free |
| Market: | WQorldwide |
Quick Details
Specifications
High Purity 99 % Trilostane 13647-35-3 Used For antifungal
Product Name: Trilostane
Synonyms: TRILOSTANE;(2-alpha,4-alpha,5-alpha,17-beta)-4,5-epoxy-17-hydroxy-3-oxoandrostane-2-car;17-beta)-ph;4-alpha,5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril;4-alpha,5-epoxy-3,17-dihydroxy-5-alpha-androst-2-ene-2-carbonitrile;4-alpha-5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril;androstane-2-carbonitrile,4,5-epoxy-17-hydroxy-3-oxo-,(2-alpha,4-alpha,5-al;modrenal
CAS: 13647-35-3
MF: C20H27NO3
MW: 329.43
EINECS: 237-133-0
Chemical Properties Tan Crystals
Usage An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer
Usage antifungal, inhibits mitosis in metaphase
Trilostane Specifications
Trilostane Description
Trilostane can suppress cortical hormone synthesis process of 3 beta dehydrogenase, make cortisol, aldosterone synthesis reduce, clinical used in the treatment of Cushing syndrome(cortisol increase disease) and primary aldosteronism,the effect is not good than testosterone metyrapone. This product has significantly reduced blood testosterone level role, may relevant to its inhibit synthetic.
Product Name: Trilostane
Synonyms: TRILOSTANE;(2-alpha,4-alpha,5-alpha,17-beta)-4,5-epoxy-17-hydroxy-3-oxoandrostane-2-car;17-beta)-ph;4-alpha,5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril;4-alpha,5-epoxy-3,17-dihydroxy-5-alpha-androst-2-ene-2-carbonitrile;4-alpha-5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril;androstane-2-carbonitrile,4,5-epoxy-17-hydroxy-3-oxo-,(2-alpha,4-alpha,5-al;modrenal
CAS: 13647-35-3
MF: C20H27NO3
MW: 329.43
EINECS: 237-133-0
Chemical Properties Tan Crystals
Usage An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer
Usage antifungal, inhibits mitosis in metaphase
Trilostane Specifications
| Test Items | Specification | Test Results | |
| Appearance | white oralmost white,crystalline powder | Conform | |
| Solubility |
Freely soluble in water,practically insoluble or very slightly soluble in alcohol and in methylene chloride. |
Conform | |
| Identification | A |
The UV absorption spectrum of the sample shows an absorption maximum at 276nm.The specific absorbance at the Maximum is55 to 64. |
Conform |
| B | Infraed absorption spectrophotometry. | Conform | |
| C |
Chromatogram obtained with test solution (b) is similar in position color & size to the principal spot in the chromatogram obtained with the reference solution. |
Conform | |
| D | An orange-red color develop in methylene chloride layer. | Conform | |
| E | It geves reaction (a) of sulphates. | Conform | |
| Appearance of solution |
Solution S is clear and not more intensely coloured than reference solution in BY6. |
Conform | |
| Optical rotation | negative 0.10° to +0.10°determined on solution S. | +0.01° | |
| Acidity or alkalinity |
NMT 0.4ml of 0.01M HCL is required to change the color of the indicator to red. |
Conform | |
| Related substances | Impurity J ≤0.20% | Conform | |
| Any other impurity ≤0.30% | Conform | ||
| Total impurity ≤1.0% | Conform | ||
| Boron | ≤50ppm | Conform | |
| Sulphated ash | ≤0.10% | 0.06% | |
| Loss on drying | ≤0.5% | 0.30% | |
| Assay(on dried basis) | 98.0~101.0% | 99.5% | |
Trilostane Description
Trilostane can suppress cortical hormone synthesis process of 3 beta dehydrogenase, make cortisol, aldosterone synthesis reduce, clinical used in the treatment of Cushing syndrome(cortisol increase disease) and primary aldosteronism,the effect is not good than testosterone metyrapone. This product has significantly reduced blood testosterone level role, may relevant to its inhibit synthetic.
