Purity: | 99 |
---|---|
Model Number: | 979-32-8 |
Brand Name: | NJBN STEROID |
Grade Standard: | Medicine Grade |
Type: | Vitamins, Amino Acids and Coenzymes |
Place of Origin: | China (Mainland) |
EINECS No.: | 213-559-2 |
MF: | C23H32O3 |
Other Names: | Estradiol valerate |
CAS No.: | 979-32-8 |
Sample: | Free |
Market: | Worldwide |
Quick Details
Specifications
99% High Purity Estradiol valerate 979-32-8 Anti Estrogen Steroids
Estradiol valerate
Estradiol Valerate description
1.Estradiol valerateIs a synthetic ester, specifically the 17-pentanoyl ester, of the natural estrogen, 17β-estradiol. It was first introduced, as Delestrogen by Squibb in the United States, in 1954,and along with estradiol benzoate (1936) and estradiol cypionate (1952), has since become one of the most widely used esters of estradiol.
2.upon ingestion, regardless of the route of administration, estradiol valerate behaves as a prodrug, being cleaved by esterases in blood plasma and the liver into 17β-estradiol and valeric acid. however, compared to estradiol itself, estradiol valerate is absorbed more slowly and possesses a longer duration, especially when given in an oil solution via intramuscular injection (in which it acts as a depot). As a result, it can be administered less frequently.
Estradiol valerate COA
Usage of Estradiol valerate
1.Estradiol valerate is anti estrogen steroids which is used in Hormone Replacement Therapy in postmenopausal women who have had a hysterectomy Estradiol valerate contains a hormone which is similar to the hormone oestrogen that is produced by the body. When women go through the menopause, levels of oestrogen become low. this leads to symptoms such as hot flushes, night sweats and dryness of the vagina. Estradiol valerate helps to replace the low levels of oestrogen which may help to relieve the symptoms of the menopause. this is known as hormone replacement therapy.
2.Estradiol valerate is a female estrogen hormone. It works by replacing natural estrogens in a woman who can no longer produce enough estrogen. It works for advanced prostate cancer by antagonizing male hormones. Treating certain symptoms of menopause ( eg, hot flashes, vaginal itching, burning, or dryness ) . It is used to treat low levels of estrogen caused by certain conditions. It may be used to treat certain types of prostate cancer ( advanced androgen dependent ) . It may also be used for other conditions as determined by your doctor.
Estradiol valerate
Product name | Estradiol valerate |
CAS NO | 979-32-8 |
Purity | 99% |
MF | C23H32O3 |
MW | 356.5 |
EINECS | 213-559-2 |
Appearance | White Powder |
Usage | Estradiol derivative, Anti Estrogen Steroids |
Synonyms | 3,5(10)-triene-3,17-diol(17-beta)-estra-17-pentanoate;atladiol;b-estradiol17-valerate;deladiol;delah Ormoneunimatic;delestrogen; Delestrogen4x;dura-estradiol |
Categories | Steroids;Intermediates&Fine-Chemicals;Pharmaceuticals; Progestogen-estrogen;DELESTRGEN;Hormone Drugs |
Estradiol Valerate description
1.Estradiol valerateIs a synthetic ester, specifically the 17-pentanoyl ester, of the natural estrogen, 17β-estradiol. It was first introduced, as Delestrogen by Squibb in the United States, in 1954,and along with estradiol benzoate (1936) and estradiol cypionate (1952), has since become one of the most widely used esters of estradiol.
2.upon ingestion, regardless of the route of administration, estradiol valerate behaves as a prodrug, being cleaved by esterases in blood plasma and the liver into 17β-estradiol and valeric acid. however, compared to estradiol itself, estradiol valerate is absorbed more slowly and possesses a longer duration, especially when given in an oil solution via intramuscular injection (in which it acts as a depot). As a result, it can be administered less frequently.
Estradiol valerate COA
Items | Results | Standard |
Characteristics |
White crystalline powder |
White crystalline powder |
Identification | Conforms | IR |
Melting point | 147.6oC | 143~150oC |
Specific optical rotation | +44.1° | +41~+47° |
Water | 0.02% | ≤0.1% |
Limit of estradio | 0.4% | ≤1.0% |
Ordinary impurities | ≤1% | ≤2% |
Free acid | 0.32% | ≤0.5% |
Assay | 100.80% | 98.0~102.0% |
Micron | 100%≤20um | 100%≤20um |
Usage of Estradiol valerate
1.Estradiol valerate is anti estrogen steroids which is used in Hormone Replacement Therapy in postmenopausal women who have had a hysterectomy Estradiol valerate contains a hormone which is similar to the hormone oestrogen that is produced by the body. When women go through the menopause, levels of oestrogen become low. this leads to symptoms such as hot flushes, night sweats and dryness of the vagina. Estradiol valerate helps to replace the low levels of oestrogen which may help to relieve the symptoms of the menopause. this is known as hormone replacement therapy.
2.Estradiol valerate is a female estrogen hormone. It works by replacing natural estrogens in a woman who can no longer produce enough estrogen. It works for advanced prostate cancer by antagonizing male hormones. Treating certain symptoms of menopause ( eg, hot flashes, vaginal itching, burning, or dryness ) . It is used to treat low levels of estrogen caused by certain conditions. It may be used to treat certain types of prostate cancer ( advanced androgen dependent ) . It may also be used for other conditions as determined by your doctor.