| Purity: | 99.1%min |
|---|---|
| Model Number: | 23593-75-1 |
| Brand Name: | NJBN |
| Grade Standard: | Medicine Grade |
| Type: | Antipyretic Analgesics and NSAIDs |
| Place of Origin: | China (Mainland) |
| EINECS No.: | 245-764-8 |
| MF: | C22H17ClN2 |
| Other Names: | Lotrimin, Mycelex, Mycospoin, Tritylimidazol |
| CAS No.: | 23593-75-1 |
| Appearance: | white or off white crystalline powder |
| Category: | Active Pharmaceutical Ingredients, antifungal agent |
| Delivery: | Safely & Timely |
| Price: | Affordable |
| Quality: | Reliable |
| Advantage: | Specialized & Experienced |
| Port: | HONGKONG, SHENZHNE, SHANGHAI, NANJING |
Quick Details
Specifications
1.Clotrimazole basic infor:
Name: Clotrimazole
Other name: Lotrimin, Mycelex, Mycospoin, Tritylimidazol
Category: Active Pharmaceutical Ingredients, antifungal agent
CAS:23593-75-1
MF: C22H17ClN2
MW:344.84
EINECS:245-764-8
2. Clotrimazole Chemical properties:
Appearance: white or off white crystalline powder
Content: 99.1%min
Melting point 147-149 ° C.
Solubility: soluble in absolute ethanol, acetone, chloroform, almost insoluble in water. Odorless, tasteless, in acid solution in the rapid decomposition.
Function: Clotrimazole is Broad - spectrum antifungal agents. for systemic fungal infection, but also for local fungal infection.
Package: 25KG/drum
MOQ |
100g |
Payment |
Western Union, Money gram, T/T, Bitcoin |
Shipment |
EMS, DHL, Fedex,UPS,TNT. |
Port |
HONGKONG, SHENZHNE, SHANGHAI, NANJING |
Delivery time |
Safe & Timely, Within 24 hours after confirming the payment |
Leading time |
4~6 working days. |
Brand |
NJBN |
Manufacture |
Yes (Nanjing Bangnuo Biotechnology Co., Ltd.) |
COA |
Yes |
Price |
Affordable |
Advantage |
Specialized & Experienced |
Market |
Global distribution |
3. Clotrimazole Functions and traits
Clotrimazole has broad-spectrum antifungal activity with excellent anti-fungal activity against Epidermophyton, Trichophyton, aspergillosis, coloring fungi, Cryptococcus and Candida species.
Clotrimazole is used to treat skin infections such as athlete's foot, jock itch, ringworm, and other fungal skin infections (candidiasis). this medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Clotrimazole is an azole antifungal that works by preventing the growth of fungus.
4. Clotrimazole Mechanism
1. through reducing the activity of cytochrome P450, it inhibit the biosynthesis of ergosterol and other sterols contained in the fungal cell membrane, causing damage of the fungal cell membrane and change its permeability and causing important intracellular material leakage.
2. Clotrimazole can inhibit the biosynthesis of the fungal triglyceride and phospholipid.
3. It can still inhibit the activity of oxidase and peroxidase, leading to the over-accumulation of hydrogen peroxide inside the cell, causing fungal subcellular structures degeneration and necrosis.
4. for Candida albicans, clotrimazole can suppresses the process of its conversion from spores into invasive hyphae.
5. APIS of Antifungal Drugs
Econazole nitrate (CAS NO.68797-31-9)
Clotrimazole (23593-75-1)
Ketoconazole (65277-42-1)
Terbinafine Hydrochloride (78628-80-5)
Miconazole (22916-47-8)
Miconazole nitrate (22832-87-7)
Bifonazole (60628-96-8)
Fluconazole (86386-73-4)
Itraconazole (84625-61-6)
Polihexanide HCl (32289-58-0)
Daptomycin (103060-53-3)
6. Clotrimazole (23593-75-1) COA
Items |
Specification |
Results |
Description |
A white or off white crystalline powder |
Complies |
Identification |
IR spectrum/TLC Test |
Complies |
Solubility |
Complies |
Complies |
Related compound A |
Not more than 0.5% |
0.12% |
Imidazole |
Not more than 0.5% |
0.15% |
Loss on drying |
Not more than 0.5% |
0.15% |
Residue on ignition |
Not more than 0.1% |
0.05% |
Heavy metals |
Not more than 0.001% |
Complies |
Assay |
Not less than 98.0% and not more than 102.0% |
99.1% |
Benzene |
2ppm max |
Complies |
Toluene |
890ppm max |
Complies |
Conclusion |
Qualified | |
TAG:
Clotrimazole
Clotrimazole cream
Clotrimazole and betamethasone
Clotrimazole lozenges
Clotrimazole troche
Miconazole
Antifungal agent
CAS 23593-75-1

