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Quick Details

Purity: 99.1%min
Model Number: 23593-75-1
Brand Name: NJBN
Grade Standard: Medicine Grade
Type: Antipyretic Analgesics and NSAIDs
Place of Origin: China (Mainland)
EINECS No.: 245-764-8
MF: C22H17ClN2
Other Names: Lotrimin, Mycelex, Mycospoin, Tritylimidazol
CAS No.: 23593-75-1
Appearance: white or off white crystalline powder
Category: Active Pharmaceutical Ingredients, antifungal agent
Delivery: Safely & Timely
Price: Affordable
Quality: Reliable
Advantage: Specialized & Experienced
Port: HONGKONG, SHENZHNE, SHANGHAI, NANJING

Specifications

99% Clotrimazole 23593-75-1 Antifungal Drug powder for sale

1.Clotrimazole basic infor:

Name: Clotrimazole
Other name: Lotrimin, Mycelex, Mycospoin, Tritylimidazol
Category: Active Pharmaceutical Ingredients, antifungal agent
CAS:23593-75-1
MF: C22H17ClN2
MW:344.84
EINECS:245-764-8

2. Clotrimazole Chemical properties:

Appearance: white or off white crystalline powder
Content: 99.1%min
Melting point 147-149 ° C.
Solubility: soluble in absolute ethanol, acetone, chloroform, almost insoluble in water. Odorless, tasteless, in acid solution in the rapid decomposition.
Function: Clotrimazole is Broad - spectrum antifungal agents. for systemic fungal infection, but also for local fungal infection.
Package: 25KG/drum

MOQ

100g

Payment

Western Union, Money gram, T/T, Bitcoin

Shipment

EMS, DHL, Fedex,UPS,TNT.

Port

HONGKONG, SHENZHNE, SHANGHAI, NANJING

Delivery time

Safe & Timely, Within 24 hours after confirming the payment

Leading time

4~6 working days.

Brand

NJBN

Manufacture

Yes (Nanjing Bangnuo Biotechnology Co., Ltd.)

COA

Yes

Price

Affordable

Advantage

Specialized & Experienced

Market

Global distribution


3. Clotrimazole Functions and traits

Clotrimazole has broad-spectrum antifungal activity with excellent anti-fungal activity against Epidermophyton, Trichophyton, aspergillosis, coloring fungi, Cryptococcus and Candida species.
Clotrimazole is used to treat skin infections such as athlete's foot, jock itch, ringworm, and other fungal skin infections (candidiasis). this medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Clotrimazole is an azole antifungal that works by preventing the growth of fungus.

4. Clotrimazole Mechanism

1. through reducing the activity of cytochrome P450, it inhibit the biosynthesis of ergosterol and other sterols contained in the fungal cell membrane, causing damage of the fungal cell membrane and change its permeability and causing important intracellular material leakage.
2. Clotrimazole can inhibit the biosynthesis of the fungal triglyceride and phospholipid.
3. It can still inhibit the activity of oxidase and peroxidase, leading to the over-accumulation of hydrogen peroxide inside the cell, causing fungal subcellular structures degeneration and necrosis.
4. for Candida albicans, clotrimazole can suppresses the process of its conversion from spores into invasive hyphae.

5. APIS of Antifungal Drugs

Econazole nitrate (CAS NO.68797-31-9)
Clotrimazole (23593-75-1)
Ketoconazole (65277-42-1)
Terbinafine Hydrochloride (78628-80-5)
Miconazole (22916-47-8)
Miconazole nitrate (22832-87-7)
Bifonazole (60628-96-8)
Fluconazole (86386-73-4)
Itraconazole (84625-61-6)
Polihexanide HCl (32289-58-0)
Daptomycin (103060-53-3)


6. Clotrimazole (23593-75-1) COA

Items

Specification

Results

Description

A white or off white crystalline powder

Complies

Identification

IR spectrum/TLC Test

Complies

Solubility

Complies

Complies

Related compound A

Not more than 0.5%

0.12%

Imidazole

Not more than 0.5%

0.15%

Loss on drying

Not more than 0.5%

0.15%

Residue on ignition

Not more than 0.1%

0.05%

Heavy metals

Not more than 0.001%

Complies

Assay

Not less than 98.0% and not more than 102.0%

99.1%

Benzene

2ppm max

Complies

Toluene

890ppm max

Complies

Conclusion

Qualified


Clotrimazole 23593751 Antifungal Drug powder for sale

TAG:

Clotrimazole
Clotrimazole cream
Clotrimazole and betamethasone
Clotrimazole lozenges
Clotrimazole troche
Miconazole
Antifungal agent
CAS 23593-75-1