D-mannose

Introduction
Mannose is not well metabolized in humans.Therefore, it does not significantly enter the carbohydrate metabolism when taken orally, and although traces of exogeneously introduced mannose have been detected in all body tissues, using radioactive markers, in a well hydrated mammal, although further studies are necessary, 90% of mannose ingested is excreted unconverted into the urine within 30 - 60 minutes, with 99% of the remainder being excreted within the following 8 hours. There is no significant increase in blood-glucose levels during this time.
Mannose is present in numerous glycoconjugates including N-linked glycosylation of proteins. C-mannosylation is also abundant and can be found in collagen-like regions. Mannose is a C-2 epimer of glucose and displays a 4C1 pucker in the solution ring form.
Recombinant proteins produced in yeast may be subject to mannose addition in patterns different from those used by mammalian cells. this difference in recombinant proteins from those normally produced in mammalian organisms may influence the effectiveness of vaccines.

Function
1) Regulate the immune system
2) Increase the wound healing
3) Inhibit tumor's growth and metastasis
4) Anti-inflammatory effect 
5) Avoid the bacterial infection such as urinary tract infection 
 
Application
D-mannose is used as sugar nutrients in the clinical and has a good efficacy in treating diabetes mellitus,obesity,constipation and high cholesterol.
It is also used as the additive in food and drinks and useful in health care industry. 

Basic Information

1)English Name	D-mannose,mannose
2)Botanical Source	Fruit Peel
3)Specification	99% by HPLC
4)CAS No.	3458-28-4
5)Molecular Formula	C6H12O6
6)Molecular Weight	180.16
7)Appearance	White crystalline powder
8)Mesh Size	80 Mesh