Purity: | >99% |
---|---|
Brand Name: | NJBN STEROID |
Grade Standard: | |
Type: | |
CAS No.: | 50-41-9 |
Model Number: | 50-41-9 |
Place of Origin: | China (Mainland) |
EINECS No.: | 200-035-3 |
MF: | C32H36ClNO8 |
Other Names: | Clomid |
Classification: | High Purity Reagents |
Standard: | Standard |
Usage: | An unducer of ovulation. A gonad-stimulating principle,Synthetic estrogen agonist antagonist. Gonad-stimulating principle) |
Delivery: | Express courier |
Quick Details
Specifications
Anti Estrogen Steroids Quick Detail:
Product Name | Clomifene citrate(Anti Estrogen Steroids) |
CAS NO | 50-41-9 |
Appearance | White powder |
Alias | Serophene; pergotime; clomphid; Clomid |
MW | 598.08 |
MF | C32H36ClNO8 |
EINECS | 200-035-3 |
Synonyms | SEROPHENE;PERGOTIME;CLOMPHID;CLOMID;CLOMIFENECITRATE;CLOMIPHENE CITRATE;CLOMIPHENE CITRATE SALT;-[4-(2-CHLORO-1,2-DIPHENYLETHENYL) |
Place of origin | China |
Package | 1kg/aluminium foil bag or as required |
Shipping | EMS, DHL, TNT, FedEx, UPS |
Delivery time | Within 24 hours upon receipt of payment. |
Usege | An unducer of ovulation. A gonad-stimulating principle,Synthetic estrogen agonist antagonist. Gonad-stimulating principle) |
Anti Estrogen Steroids Specification:
COA:
Tests | Analysis Standard | Results |
Identification | Conform | Conform |
Absorbance | 0.30% | Conform |
Specific Rotation | +39~ +43 | +39.5 |
Chromatography Purity | Conform | Conform |
17-Isomer | 0.50% | 0.40% |
Organic Volatile Impurities | Conform | Conform |
Loss on Drying | 0.50% | 0.32% |
Residue on Ignition | 0.10% | 0.01% |
Assay | 97~101% | 99.02% |
Conclusion | Be Conform with USP31 Standard |
Anti Estrogen Steroids Product Description:
- 1.Clomiphene citrate is a kind of Anti Estrogen Steroids drugs. It has strong anti-estrogenic effect and weak estrogenic effects, and is easily absorbed in the gastrointestinal tract, and can be slowly excreted through the liver into the bile duct.It is clinically useful in the treatment of women infertility with a certain level of estrogen but being anovulatory or less ovulatory and treatment of male infertility with luteal phase defect or few sperm.
- 2.It can also used for testing ovarian function and probing the dysfunction of male hypothalamus (pituitary) gonadal axis. the mechanism of action is to competitively bind to the hypothalamus estrogen receptor binding site for taking effect. Estrogen is displaced out from these areas, then the hypothalamus will be aware of the apparent lack of circulating estrogen, leading to the release of gonadotropin hormone for stimulation of follicle stimulating hormone (FSH) and luteinizing hormone (LH) secretion with whom to trigge the normal menstrual cycle.
- 3.Clomiphene citrate is a kind of triphenylethylene derivatives with its structure being similar to estrogen and has a strong anti-estrogen but weak estrogenic activity. the ovulation induction mechanism of this product is to promote an increase in the secretion of pituitary gonadotropins; gonadotropin stimulates the follicle growth and maturation inside the ovary, further causing production and secretion of luteinizing hormone with a clinical pregnancy curing rate of 35% for patients suffering ovulation disorders. however, for patients with primary pituitary or ovarian dysfunction, such as primary amenorrhea, it is usually for applying this drug for treatment.
Anti Estrogen Steroids Applications:
- 1.It is usually for applying this drug for treatment. In addition, anovulation caused by factors of other organs (such as thyroid, adrenal dysfunction) is not suitable for subjecting to this treatment. Clomiphene citrate has an effect of promoting the sperm production of men which is clinically used for the treatment azoospermia. The prerequisite for clinical application is a certain function in ovarian and a normal or a bit lower hormone levels.Clomifene citrate may also be used in cases of unexplained infertility.
- 2.It is mainly used for the treatment of anovulatory or inadequate luteal malfunction; infertility women who hope for pregnancy. At the 3-5 days of menstrual bleeding or progesterone withdrawal bleeding, orally administrate 50 mg daily and continuously take for five days. Usually ovulation occurs at about 7 days after stopping drugs when having intercourse is easy to increase the pregnancy rate. At appropriate indications, most patients can ovulate in the first cycle of treatment, for patients of long-term amenorrhea, their endometrial is not sensitive enough which requires two to three cycles of treatment for induction menstruation.