Introduction:

Adrafinil is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention in elderly patients. It is also used off-label by individuals wishing to avoid fatigue, such as night workers or others who need to stay awake and alert for long periods of time.

Adrafinil has been found to increase exploratory behavior and alertness in animals (Siwak, 2000). It also increased speed of learning and decreased errors in the performance of a task (Milgram, 2000). Additionally, Adrafinil increased the nocturnal activity of rhesus monkeys between 2- and 4-fold, without a sedative effect during the post-treatment phase (Milhaud, 1985). What this means is that the rhesus monkeys were 2 to 4 times more active while awake during the night, but did not revert to sluggishness once the Adrafinil was removed!

Originally developed to increase wakefulness in narcoleptics, adrafinil is a truly potent supplement and should be used with discretion. Do not a consume a higher dosage than 400mg of Adrafinil as it may elevate liver enzymes. If you have any health concerns, please consult a physician.

Adrafinil is best taken on an empty stomach. Unless necessary, initially avoid taking adrafinil before bed to avoid potentially interfering with sleep, as it is stimulatory. Effects can typically be felt in approximately an hour, and the duration can be 3 to 4 hours.