1148148-01-9
BrettPhos-Pd-G1, Methyl t-Butyl Ether Adduct
Synonym: (BrettPhos) palladium(II) phenethylamine chloride, 
BrettPhos Palladacycle, BrettPhos precatalyst, 
Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2,4, 6-triisopropyl-1,1-biphenyl][2-(2-aminoethyl)phenyl]palladium(II)

CAS 1148148-01-9
Formula: C43H63ClNO2PPd
Formula Weight: 798.81 g/mol
ISO9001 Manufacturer 
Standard laboratory 
Ligands catalysts synthesis pharmaceutical compounds electronic intermediates

Appearance (Color) White to Light Yellow
Assay  97%
Mp  198-204 °C
Caution: air sensitive, refrigeration
Shelf life:12 month 
Supplier: LPBchem-Benjamin

Related Categories
Buchwald 1st Generation Palladacycles, Buchwald Ligands and Complexes, Catalysis and Inorganic Chemistry, Chemical Synthesis, Cross-Coupling,
Homogeneous Pd Catalysts, Other Palladacycle Coupling Catalysts, Palladium Catalysts

General description
BrettPhos Pd G1 is a Buchwald first generation (G1) palladacycle precatalyst that can be used in cross-coupling reactions for the formation of C-C, CN, CO, CF, CCF3, and CS bonds. the formation of the active Pd(0) species in the G1 precatalyst is easy to generate, requiring merely a deprotonation with a base. the resulting catalyst is very active, even at temperatures down to?40 °C, and can be used in a variety of cross-coupling protocols.

Application
Catalyst for:
-C,N-cross coupling of unprotected 3-halo-2-aminopyridines with primary and secondary amines
-Amination reaction
- N-arylation of aminophenols