| Purity: | 99% |
|---|---|
| Brand Name: | Lingding |
| Grade Standard: | Medicine Grade, |
| Type: | Vitamins, Amino Acids and Coenzymes |
| CAS No.: | 171596-29-5 |
| Place of Origin: | China (Mainland) |
| EINECS No.: | 687-782-2 |
| MF: | C22H19N3O4 |
| Other Names: | CIALIS |
| Appearance: | White to off White Powder |
| Grade: | Pharma |
| Storage: | Cool Dry Place |
| Shelf Life: | 2 Years |
Quick Details
Specifications
| Melting point | 298-300°C |
| Alpha | D20 +71.0° |
| Boiling point | 679.1±55.0 °C(Predicted) |
| Density | 1.51±0.1 g/cm3(Predicted) |
| Fp | 2℃ |
| Storage temp. | Hygroscopic, -20?C Freezer, under Inert Atmosphere |
| Solubility | DMSO: soluble20mg/mL, clear |
| Form | Powder |
| pka | 16.68±0.40(Predicted) |
| Color | White to beige |
| Optical activity | [α]/D +68 to +78°, c = 1 in chloroform-d |
Tadalafil (market name " Cialis" or " Adcirca" ) is a kind of PDE5 inhibitor used for the treatment of erectile dysfunction, benign prostatic hypertrophy and pulmonary arterial hypertension. the effect of Tadalafil is relaxing the blood vessels muscles and increasing the blood flow into the corpus cavernosum. the mechanism of action of tadalafil is through inhibiting the activity of the cGMP specific phosphodiesterase type 5 (PDE5). PDE5 degrades cGMP in the corpus cavernosum located around the penis. Therefore, tadalafi leads to the increased concentration of cGMP which further causes the smooth muscle relaxation and increased blood flow into the corpus cavernosum. Some clinical studies also implied that tadalafil could improve endothelia function in men with increased cardiovascular risk and lower the urinary tract symptoms secondary to benign prostatic hyperplasia.
Application
Analgesic, norepinephrine uptake blocker, mu-opiod receptor agonist.A phosphodiesterase 5 inhibitor.Tadalafil is used for the treatment of erectile dysfunction.
Packaging Details
25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients
Port:TIANJIN
Lingding Biotechnology Co., Ltd. is a professional business company,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
the company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
