| Place of Origin: | China (Mainland) |
|---|
Quick Details
Specifications
Rat OPG(Osteoprotegerin) ELISA Kit Basic Information
Feiyue's Rat OPG is an ELISA reagent for detection of Chicken OPG in serum, plasma or cell with sensitivity, specificity and consistency.
Rat OPG(Osteoprotegerin) Introduciton
Osteoprotegerin (OPG), also known as osteoclastogenesis inhibitory factor (OCIF) or tumour necrosis factor receptor superfamily member 11B (TNFRSF11B), is a cytokine receptor of the tumour necrosis factor (TNF) receptor superfamily encoded by the TNFRSF11B gene. OPG was first discovered as a novel secreted TNFR related protein that played a role in the regulation of bone density and later for its role as a decoy receptor for Receptor Activator of Nuclear Factor kappa-B ligand (RANKL). OPG also binds to TNF-related apoptosis-inducing ligand (TRAIL) and inhibits TRAIL induced apoptosis of specific cells, including tumour cells. Other OPG ligands include syndecan-1, glycosaminoglycans, von Willebrand Factor, and Factor VIII-von Willebrand Factor complex.
Rat OPG(Osteoprotegerin) ELISA Kit Test method
this kit uses sandwich ELISA to detect the concentration of Rat OPG.
Rat OPG-specific monoclonal antibody has been pre-coated in the wells of the supplied microplate. Standards samples and controls are added to interact with the immobilized antibody. A sandwich complex is formed by additional anti-Rat OPG antibody with HRP-Streptavidin. TMB solution is added to react with the sandwich for ming optical signal measured by microplate reader. the concentration of Rat OPG in the sample can be calculated by comparing the absorbance of the sample with the standard curve.
Product Name |
Rat OPG(Osteoprotegerin) ELISA Kit |
Catalog NO. |
FY-ER4167 |
Alias |
OPG; Osteoprotegerin; OCIF; TNFRSF11B; OPGtumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin; TR1; tumor necrosis factor receptor superfamily; member 11b |
Application |
OPG ELISA Kit allows for the in vitro quantitative determination of OPG concentrations in serum, plasma, tissue homogenates and other biological fluids. |
Size |
48T, 96T |
Storage |
2-8 ℃ for 6 months |
Sensitivity |
<37.5pg/ml |
Species |
Rat |
UniProt ID |
O08727 |
CV (%) |
Intra-Assay: CV<8% |
Note |
for Research Use Only |
Rat OPG(Osteoprotegerin) Introduciton
Osteoprotegerin (OPG), also known as osteoclastogenesis inhibitory factor (OCIF) or tumour necrosis factor receptor superfamily member 11B (TNFRSF11B), is a cytokine receptor of the tumour necrosis factor (TNF) receptor superfamily encoded by the TNFRSF11B gene. OPG was first discovered as a novel secreted TNFR related protein that played a role in the regulation of bone density and later for its role as a decoy receptor for Receptor Activator of Nuclear Factor kappa-B ligand (RANKL). OPG also binds to TNF-related apoptosis-inducing ligand (TRAIL) and inhibits TRAIL induced apoptosis of specific cells, including tumour cells. Other OPG ligands include syndecan-1, glycosaminoglycans, von Willebrand Factor, and Factor VIII-von Willebrand Factor complex.
Rat OPG(Osteoprotegerin) ELISA Kit Test method
this kit uses sandwich ELISA to detect the concentration of Rat OPG.
Rat OPG-specific monoclonal antibody has been pre-coated in the wells of the supplied microplate. Standards samples and controls are added to interact with the immobilized antibody. A sandwich complex is formed by additional anti-Rat OPG antibody with HRP-Streptavidin. TMB solution is added to react with the sandwich for ming optical signal measured by microplate reader. the concentration of Rat OPG in the sample can be calculated by comparing the absorbance of the sample with the standard curve.