| Brand Name: | An qing |
|---|---|
| Appearance: | Yellow |
| Purity: | 98% |
| Grade Standard: | Industrial Grade |
| CAS No.: | 1420477-60-6 |
Quick Details
Specifications
Acalabrutinib (ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively
) and no activity against EGFR
) and no activity against EGFR