Introduction of cepharanthine

the cepharanthine is a two-benzyl isowaline alkaloid isolated and extracted from the tetragoniaceae plants.It has the functions of anti-tumor,anti-malarial,antibacterial,and immune function regulation.Modern research suggests that it also has the functions of stimulating the reticuloendothelial system,activating hematopoietic tissue,and promoting the proliferation of bone marrow tissue.Therefore,cepharanthine is considered to be a low-toxic and effective leukocyte-raising drug.At present,Chinese scientists have found that a very small amount of cepharanthine can prevent the expansion and spread of the new coronavirus.

the role of cepharanthine

CepharanthineHas potential antitumor effect.the single application of cepharanthine can play an anti-tumor effect by inhibiting the proliferation of tumor cells and enhancing the body's immunity.What is more promising is that cepharanthine combined with chemotherapeutic drugs can improve the efficacy of chemotherapy by reducing the drug resistance of cells.The main mechanism may be that cepharanthine can increase the accumulation of anticancer drugs in cells by interfering with the function of the plasma addition,cepharanthine can also improve the sensitivity of tumor cells to radiotherapy.Direct anti-tumor effect of cepharanthine:cepharanthine can enhance the body's anti-tumor ability by enhancing the body's immune response.Macrophages can specifically recognize and kill tumor cells and play a crucial role in anti-tumor immunity.however,in individuals with tumorigenesis,macrophages are often inhibited.Chrysanthin can activate macrophages,which may be related to its effect on tumor therapy.

on May 10,2022,a new drug for the treatment of COVID-19 discovered by Chinese scientists was granted a national invention patent.the patent specification shows that 10μM(micromol/L)of cepharanthine inhibits the replication of coronavirus by a factor of 15,393.

Application fields of cepharanthine

Applied in medicine(COVID-19).