Milk Thistle Extract Silymarin 80%
Silymarin (80%) is a standardized extract derived from the seeds of the Milk Thistle plant (Silybum marianum).

 

Botanical Source: Milk Thistle (Silybum marianum)

Extraction Part: Seeds

Extraction Method: Supercritical CO2 extraction

Extraction Solvent: Carbon dioxide

Detection Method: HPLC

Odor: Odorless

Color: Yellowish-brown

Appearance: Powder

CAS Number: 65666-07-1

Molecular Formula: C25H22O10

Molecular Weight: 482.44 g/mol

 

PHarmacologicalPRoperties

1. Hepatoprotective Activity: Silymarin has been extensively studied for its hepatoprotective activity, which refers to its ability to protect the liver from damage caused by toxins and other harmful substances. Silymarin exerts its hepatoprotective effects through multiple mechanisms, including inhibition of oxidative stress, modulation of inflammation, and regulation of cellular signaling pathways. Silymarin is widely used to treat liver diseases such as hepatitis, cirrhosis, and fatty liver disease, and it has been shown to improve liver function and reduce liver damage in numerous clinical studies.

 

2. Antioxidant Activity: Silymarin is a potent antioxidant that can scavenge free radicals and prevent oxidative damage to cells and tissues. Silymarin acts as an antioxidant by inhibiting the production of reactive oxygen species (ROS), enhancing the activity of antioxidant enzymes, and chelating metal ions that can catalyze oxidative reactions. the antioxidant activity of silymarin has been shown to protect against a variety of conditions associated with oxidative stress, including cancer, cardiovascular disease, and neurodegenerative disorders.

 

3. Anti-Inflammatory Activity: Silymarin has been shown to have anti-inflammatory activity in various experimental models, and it has been suggested that this activity may contribute to its hepatoprotective effects. Silymarin inhibits the production of inflammatory mediators such as cytokines and chemokines, and it also modulates the activity of immune cells such as macrophages and T cells. Silymarin has been shown to reduce inflammation in the liver, lungs, and other tissues, and it may have potential as a treatment for inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.

 

4. Anticancer Activity: Silymarin has been shown to have anticancer activity in numerous preclinical studies, and it may have potential as a cancer chemopreventive agent or as an adjuvant therapy for cancer. Silymarin exerts its anticancer effects through multiple mechanisms, including inhibition of cell proliferation, induction of apoptosis, and modulation of cell signaling pathways. Silymarin has been shown to have anticancer effects against various types of cancer cells, including breast, prostate, lung, colon, and skin cancer cells.

 

5. Antimicrobial Activity: Silymarin has been shown to have antimicrobial activity against a variety of bacterial, fungal, and viral pathogens. Silymarin exerts its antimicrobial effects through multiple mechanisms, including disruption of cell membranes, inhibition of viral replication, and modulation of host immune responses. Silymarin has been shown to be effective against several antibiotic-resistant pathogens, and it may havethePotential as a natural alternative to conventional antimicrobial agents.