Product Name: Grape seed extract Specification：proanthocyanidins>95% Test Method: UV Packing: 25Kg/drum Grape Seed (skin) P.E. Latin name: Vitis vinifera L. Chinese Pin -Yin name: Pu Tao Zi Family: vitaceae Genus: vitis Part used: Seed (skin) History: Grape Seed (skin) extract is an extract from the seed (skin)s of grapes. The seed (skin) s left over from the production of wine or juice are harvested, ground and extracted. They have a high content of compounds known as OPCs (oligomeric proanthocyanidins). Since French researcher, Dr. Jack Masquelier isolated OPCs from peanut skin in 1947, OPCs is found in many plants and has been declared to be a potent antioxidant of non-toxic, non-mutagenic, non-carcinogenic, and free of side effects according to a review of numerous researches. Function: The antioxidant capacity of Grape Seed (skin) Extract comes from proanthocyanidins (oligomeric proanthocyanidins) (OPCs). With an antioxidant power 20 times stronger than Vitamin C and 50 times stronger than Vitamin E, OPCs is known as a powerful antioxidant to neutralize free radicals, which play a major role in degenerative diseases, cardiovascular diseases, impaired vision, sun damage and premature aging. 1. Cardiovascular Diseases Researches have assured that OPCs helps strengthen capillaries, arteries and veins, which endows it several important clinical applications. OPCs appear to stabilize the walls of blood vessels, reduce inflammation, and generally support tissues containing collagen and elastin. 1). Atherosclerosis: It has been proved that the oxidation of LDL plays an important role in atherosclerosis. By its excellent antioxidant activity, OPCs eliminates damages that free radicals, as well as collagenase and elastinase do to the arteries, thus prevents or reverses atherosclerosis. Animal evidence suggested that OPCs could slow or reverse atherosclerosis. 2). Venous Insufficiency (Varicose Veins) Varicose Veins refers to the situation when blood pools in the legs, causing pain, heaviness, swelling, fatigue, and unsightly visible veins. By strengthening capillary and reduce capillary osmosis, OPCs can relieve the pain and swelling of venous insufficiency. For the same reason, OPCs is recommended as a treatment for hemorrhoids as well. There is also some evidence that OPCs can be useful for the swelling that often follows injuries or surgery. OPCs appear to speed the disappearance of swelling, by strengthening damaged blood and lymph vessels that are leaking fluid. A double-blind placebo-controlled study of 92 subjects found that OPCs, taken at a dose of 100 mg 3 times daily, significantly improved major symptoms, including heaviness, swelling, and leg discomfort. [21] Over a period of 1 month, 75% of the participants treated with OPCs improved substantially. Another placebo-controlled study that enrolled 364 individuals with varicose veins also found that treatment with OPCs produced results superior to those of placebo. 3). Retinopathy/Vision Improvement The capacity of OPCs in strengthening capillary and reduce capillary osmosis is effective for patients suffering from stroke and retinopathy. OPCs has been proved to improve retinopathy caused by diabetics, atherosclerosis, inflammation and aging. It has also been reported that OPCs can speed vision recovery after strong light, and improve vision acuity of those who suffer from eye fatigue because of long-time computer using. A 6-week, controlled (but not blinded) study eval