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Purity: >99%
Model Number: CAS: 82009-34-5
Brand Name: NJBN STEROID
Grade Standard: Medicine Grade
Type: Auxiliaries and Other Medicinal Chemicals
Place of Origin: China (Mainland)
EINECS No.: 279-875-8
MF: C16H26N2O5S
Other Names: CILASTATIN;(z)-7-[(2s)-2-amino-3-hydroxy-3-oxopropyl]sulfanyl-2-[[(1s)
CAS No.: CAS: 82009-34-5
Payment Terms:: T/T, Western Union, Money Gram
Delivery Ways: EMS, Hkems, TNT, DHL, FedEx, UPS etc.
Shipment Time: 3-5 Working Days After Receiving Payment
Usage: Prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.

Specifications

Active Pharmaceutical Ingredient CAS for spectrum antibiotic


Quick Detail:

Product Name:

Synonyms:CILASTATIN;(z)-7-[(2s)-2-amino-3-hydroxy-3-oxopropyl]sulfanyl-2-[[(1s)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid;(r-(r*,s*-(z)))-)carbonyl)amino);mk-791;Cilastain;(2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid;Cilastatin acid;(Z)-7-[(2S)-2-Amino-3-hydroxy-3-oxopropyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid

CAS NO. :

MF : C16H26N2O5S

EINECS:279-875-8

MW : 358.45

Appearance : White to Light-Yellow Crystalline Powder

Purity : >99%

Grade : Pharmaceutical Grade & Veterinary Grade

Storage: Closed, shading preservation

Brand Name:NJBN STEROID

Delivery time : Within 24 hours upon receipt of payment

Shipment : EMS, DHL, TNT, FedEx, UPS

Usage :Prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.

Description:

Cilastatinis a chemical compound which inhibits the humanenzymedehydropeptidase.

Dehydropeptidase is an enzyme found in thekidneyand is responsible for degrading theantibioticimipenem. Cilastatin can therefore be combinedintravenouslywith imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect. Imipenem alone is an effective antibiotic and can be given without the cilastatin. Cilastatin itself does not have antibiotic activity although it has been proved to be active against a zinc-dependentbeta-lactamasethat usually confer antibiotic resistance to certain bacteria; more precisely thecarbapenemfamily of antibiotics. This property is due to the physico-chemical similarities betweenmembrane dipeptidase(MDP), the compound it is usually set to target, and the bacterial metallo-beta-lactamase carried by the CphA gene[1]Therefore, Cilastatin is considered abeta-lactamase inhibitor, not an antibiotic per se.


Application:

Prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct


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3. Delivery:By courier ( EMS , DHL , Fedex , UPS ,TNT) is preferrable , bulk order can be negotiable
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